2. Signaling Pathways
  3. Cell Cycle/DNA Damage
  4. DNA Alkylator/Crosslinker
  5. DNA Alkylator/Crosslinker Inhibitor

DNA Alkylator/Crosslinker Inhibitor

DNA Alkylator/Crosslinker Inhibitors (4):

Cat. No. Product Name Effect Purity
  • HY-16405
    PR-104
    		Inhibitor
    PR-104 is a selective hypoxia-activated DNA cross-linking agent and can be used for the research of multiple tumor xenograft models. PR-104, as a nitrogen mustard pre-proagent, is converted efficiently to the more lipophilic dinitrobenzamide mustards alcohol PR-104A.
  • HY-164303
    Val-Cit-PAB-DEA-Duo-DM
    		Inhibitor
    Val-Cit-PAB-DEA-Duo-DM is a drug-linker conjugate, which consists of the linker Val-Cit-PAB, the spacer DEA and the ADC toxin Duocarmycin DM (Duo-DM) (HY-130978). Val-Cit-PAB-DEA-Duo-DM can be used for the synthesis of ADC molecule.
  • HY-16406
    PR-104 sodium
    		Inhibitor
    PR-104 (sodium) is a selective hypoxia-activated DNA cross-linking agent and can be used for the research of multiple tumor xenograft models. PR-104 (sodium), as a nitrogen mustard pre-proagent, is converted efficiently to the more lipophilic dinitrobenzamide mustards alcohol PR-104A.
  • HY-136327
    Phenylacetic acid mustard
    		Inhibitor
    Phenylacetic acid mustard is the major metabolite of the cancer chemotherapeutic agent Chlorambucil (HY-13593). Chlorambucil is an alkylating agent with antitumor activity.